Pharmacy, Nursing and Health Sciences Library


Library Highlights

 Thomas S. and Harvey D. Wilmeth Active Learning Center

This is a video about the Thomas S. and Harvey D. Wilmeth Active Learning Center coming in 2017!

Fragment-Based Methods in Drug Discovery

This volume covers the techniques necessary for a successful fragment-based drug design project, beginning from defining the problem in terms of preparing the protein model, identifying potential binding sites, and the consideration of various candidate fragments for simulation. The second part discusses the technical aspects that various methods have used to simulate fragment binding to a target protein by using Monte Carlo, molecular dynamics, and docking algorithms. After simulations, fragments are assembled into molecules using a variety of approaches, which are explored next. A discussion of design strategies and consideration of drug-like properties is included as part of the design process at this stage. Finally, several examples of successful fragment-based drug design projects are presented. Written for the Methods in Molecular Biology series, this work contains the kind of detailed description and implementation advice to encourage success in the lab.

Practical and cutting-edge, Fragment-Based Methods in Drug Discovery takes into account the great accomplishments in the field to provide an ideal guide for researchers continuing to investigate this exciting area of pharmacological study.

About the Library

Map of the location of the Library
Physical Address: 

Heine Pharmacy Building Room 272
575 Stadium Mall
West Lafayette, IN 47907

Mailing Address: 

Purdue University Libraries - PNHS
504 West State Street
West Lafayette, IN 47907

(765) 494-1416
    Located on the 2nd floor of the Heine Pharmacy building (RHPH), this library contains Purdue University's health-related materials. Patrons have access to 30,000 physical volumes a collection of databases and other electronic resources , 6 ITaP computers, printers, scanner, copier, WiFi connection, and research assistance upon request.

    There is a study space both on the first floor and balcony areas with vast amounts of natural light from the tall windows.